What Antidepressants Can Cause Hair Loss? Know Your Options!

While hair loss can occur due to a variety of reasons including aging, genetics, stress, and certain medical conditions, it’s important to be aware that certain medications, including antidepressants, can also contribute to this condition. In this comprehensive guide, we’ll explore what antidepressants can cause hair loss, providing a closer look at the medications linked to this side effect and additional related information.

What antidepressants can cause hair loss?

Antidepressants can cause hair loss, specifically a type called telogen effluvium, which is a temporary hair loss triggered by factors such as stress and medication. The risk of hair loss varies among different antidepressants.

According to a comparative retrospective cohort study, bupropion has the highest risk of hair loss, while paroxetine has the lowest risk. Sertraline has also been reported to cause hair loss in some cases. Fluoxetine is another SSRI that has been associated with hair loss.

Other antidepressants that may cause hair loss include fluvoxamine, citalopram, escitalopram, duloxetine, venlafaxine, and desvenlafaxine.

The mechanism behind antidepressant-induced hair loss is not fully understood, but it is believed to be related to the drugs’ effects on the telogen phase of hair production.

It is important to note that hair loss is a relatively rare side effect of antidepressants.

If you are experiencing hair loss while taking antidepressants, it is crucial to consult with your healthcare provider before making any changes to your medication regimen.

They can help determine the cause of the hair loss and discuss alternative treatment options if necessary.

The science behind antidepressants and hair loss

Antidepressants can cause hair loss by disrupting the natural growth phases of hair. This hair loss generally occurs during the anagen phase, the active growth stage when new hair fibers are produced.

Certain antidepressants can interfere with this process, leading to a premature transition into the telogen phase (resting stage), thus resulting in hair loss.

How to manage hair loss from antidepressants?

If you notice an increase in hair loss while taking antidepressants, it’s important to consult your doctor. They may adjust your dosage or suggest alternative medications that may be less likely to cause this side effect.

Don’t stop taking your medication without consulting your doctor, as this can lead to withdrawal symptoms and a potential relapse of depression symptoms.


While it can be distressing to experience hair loss while dealing with depression, it’s crucial to remember that your mental health should always be a priority. It’s also worth noting that hair loss caused by antidepressants is usually temporary and may reverse once the medication is discontinued or changed.

Always consult with your healthcare provider for personalized advice concerning your treatment and possible side effects like hair loss. Remember, you’re not alone in this, and there are many resources and strategies available to manage both depression and hair loss effectively.

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