2023 Ultimate Hair Loss Product Comparison – Which Work Best & How To Minimise Side Effects?

Dozens of new hair loss products hit the market every year — yet few if any provide real, lasting results.

Despite this, the scientific evidence is clear: many ingredients can help fight hair loss and promote hair growth. Whether it’s by boosting blood flow to the scalp, extending the hair growth cycle, or even managing hormone levels, there are many proven ways to extend the life of your hair and even grow new ones.

This guide is designed to help you find the best and most scientifically proven hair growth solution, while minimising side effects and negative reactions.

How Do Most Hair Loss Products Work?

Most hair loss products usually work by either slowing down the hair growth cycle or altering the levels of several key hormones.

This means that your new hair can essentially get a “trigger signal” to grow again, or that existing hair strands will last longer and be less likely to fall.

Through these mechanisms, a good hair loss product can usually offer the following benefits:

1.       They can reduce the tendency for hair to fall out

2.       They can promote hair thickness and fight thinning hair

3.       They can improve the shine and appearance of existing hair

What Should You Look For In A Hair Growth Solution?

Criteria #1: It has to help manage IGF-1 levels – a key hormone associated with hair growth

Most people know that hair loss has to do with hormones – but which ones exactly? Recent clinical studies show that IGF-1 is the one of the primary hormones associated with healthy hair growth and hair longevity.

Any hair loss solution has to contribute to higher IGF-1 levels, an effective way to stop hair loss in its tracks.

Criteria #2: It has to contain ingredients with minimal side effects

According to other recent studies, many hair growth solutions can have a wide range of side effects — from irritation and acne to hormonal dysfunction and even infections.

The best way to avoid this issue is to choose a product with natural ingredients that have a long history of safety and reliability.

Criteria #3: It has to extend the hair growth cycle

Most people who struggle with hair loss are unfortunate to have a genetically shorter hair growth cycle. This means that an entire cycle for their hair might last for just a year, compared to 3 or 5 years for a person not struggling with hair loss.

Luckily, there are some scientifically proven ways to extend the hair growth cycle through effective ingredients that act directly in the scalp.

Our Special Evaluation System

The ratings in this article are based on a system of specialized criteria. In a comprehensive process, we compare the products by carefully evaluating the ingredients, safety, effectiveness, reimbursement guidelines and overall customer satisfaction. By evaluating these factors, combined with the latest studies and clinical trials, we make it easy for you to choose the best hair growth product on the market while saving both time and money.

The 4 best hair loss products on the market today

After hours of intensive research, and considering combined ratings and online reviews from customers like you, weve compiled a list of the top four hair growth products on the market.

1: Scandinavian BiolabsBio-Pilixin® Hair Growth Kit




The Bio-Pilixin® formula was developed by the well-known Danish brand Scandinavian Biolabs and is in Denmark. The mission of the company is to provide products with similar or superior benefits to pharmaceutical solutions, using exclusively naturally-derived natural ingredients with minimal side effects.

Their flagship hair growth kits for men contain 3 products — a shampoo, a conditioner, and a serum. Each product in the kit contains several clinically proven ingredients that can promote hair growth naturally.

The primary mechanism of action of the formula is through increasing IGF-1 levels, the key hair growth hormone, while lengthening the hair growth cycle through a blend of natural ingredients.

The clinical efficacy of Scandinavian BiolabsBio-Pilixin® hair growth formula has been independently evaluated by the Capillary Technology Center through the course of a 5-month study.

Here are the key clinical findings of the study, as reported by researchers after 150 days of treatment:

  • 93.3% of volunteers showed a reduction in hair loss. The average hair loss reduction was 45.75%, with a maximum hair loss reduction ot 85.08% (volunteer 26)
  • 73.3% of volunteers showed a significant improvement in hair density. Capillary density increased by up to 23.31% after the treatment.
  • 17.5% increase in the number of hair in the anagen (growth) phase after 150 days. 36.5% decrease in the number of hair in the telogen (rest) phase after treatment.
  • 80% of volunteers reported a moderate-to-intense hair loss reduction.
  • 93.3% of volunteers reported being satisfied with the hair loss treatment.

The hair growth kits are protected by an unmatched 150-day money-back guarantee, reflecting the brands confidence in their formula. Their hair growth kit is available in a mans version and a womans version

All of the ingredients in the formula have a long history of safety and have no major known side effects. This makes Scandinavian Biolabshair growth kit the safest and most effective hair growth product on the market right now.


Clinical study independently evaluated by the Capillary Technology Center

  • Increased levels of IGF-1 in the scalp, a key hormone for hair growth, 26% more effectively than minoxidil
  • An effective blend of natural ingredients to extend the hair growth cycle
  • Very few risks of powerful side effects
  • 150 days money-back guarantee


  • Can run out of stock quickly
  • Might be seen as relatively expensive for people with modest budgets, but we find the price warranted given the excellent customer feedback and clinical efficacy of active ingredients



2: ROGAINE®’s Minoxidil Products

minoxidil bottle


ROGAINE®’s products are pharmaceutical solutions typically containing 5% minoxidil. Their products are to be applied directly to the scalp. In addition to Minoxidil, the product also contains botanical extracts and emollients, as well as Alphahydroxy Acid (AHA).

Minoxidil is a scientifically studied ingredient to promote hair growth. Unfortunately, its also associated with many harmful side effects, most commonly irritation, redness, and itching. Its effectiveness is however clearly proven.

Their products feel nice and are easy to apply to the skin. Our scientific team wasnt able to find any clinical study for the other ingredients in the formula, however, which is a negative.

Overall, ROGAINE is a good pharmaceutical hair growth product but does not provide more benefits than our number one choice while exposing users to more side effects.


  • Highly concentrated minoxidil promotes hair growth
  • The foam makes it pleasant and easy to apply on the scalp
  • Quality branding and packaging


  • Incidence of side effects such as irritation, redness, and itching
  • High amounts of additives and artificial ingredients


3: Foligains Trioxidil Products


Foligains Trioxidil is a direct competitor and alternative to ROGAINE. Their core products either use Trioxidil, a minoxidil alternative and often contain natural ingredients to complement the pharmaceutically active compound.

Their offer a wide range of shampoos and conditioners as well. However, only the core 10% Trioxidil solution has clinical evidence showing it can promote hair growth. Furthermore, the strength of the scientific evidence for Trioxidil is limited compared to Minoxidil.

However, the fact that the products do not contain parabens and the most harmful additives is a big bonus. Overall, its a less effective but slightly safer version of ROGAINE, which is why we cannot rank it higher.


  • Has clinical evidence for hair loss claims
  • Relatively few additives for a pharmaceutical product
  • Easy application


  • Trioxidil is associated with many harmful side effects
  • No long-term studies


4: Grow GorgeousIntense Hair Growth Serum



We switch to a natural product for 4th place and focus on Grow Gorgeousstrongest product, their Intense Hair Growth Serum. The product uses a mix of 5 natural ingredients that promise to promote thicker hair and stimulate the roots of hair follicles.

Despite these claims, we were not able to find suitable scientific studies proving their claims that the ingredients can promote hair growth in vivo. The ingredients probably have many benefits for hair health, but we cannot conclusively agree that they will promote hair growth.

On the plus side, the serum is natural and does not contain additives — which minimizes the chances of side effects. But the lack of scientific evidence is a big problem and is why its only ranked 4th. Its also very expensive considering the low quantity of active ingredients.


  • Natural ingredients
  • No harmful additives
  • Low chances of side effects


  • Very limited scientific evidence
  • No clear mechanism to promote hair growth


Dr. Ahmad Chaudhry M.B.B.S.
Dr. Ahmad Fayyaz Chaudhry earned his MBBS degree from Punjab Medical College, Faisalabad, in 2020. During graduation, he enrolled himself in the Dermatology Ward DHQ Hospital Faisalabad for all the necessary training required to pass the bachelor's exam and encounter dermatological diseases daily. Currently, he is posted as a House Physician in the Medical Unit 3 Allied Hospital Faisalabad, where he encounters all kinds of hepatic, cardiac, neurological, and dermatological diseases daily.

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